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KMID : 0858420080100010036
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Korean Journal of Stroke
2008 Volume.10 No. 1 p.36 ~ p.40
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Magnetic Resonance Imaging Patterns of Cerebral Infarction in Patients with Malignancy: Diffusion-Weighted Imaging Study
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Kang Kyung-Wook
Park Man-Seok
Cho Ki-Hyun
Choi Seong-Min
Lee Seung-Han
Kim Byeong-Chae
Kim Joon-Tae
Kim Myeong-Kyu
Shin Cheol-Seung
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Abstract
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Background: The pathogenesis of cerebral infarction in malignancy is complex and not yet completely understood. A hyper-coagulable state, non bacterial thrombotic endocarditis and thrombotic arterial microangiopathy may be important causes of cerebral infarction in malignancy. The purpose of this study is to describe diffusion-weighted imaging (DWI) patterns of cere-bral infarction in patients with malignancy.
Methods: We analyzed 28 patients with cerebral infarction and malignancy. We reviewed medical records and retrospectively analyzed the DWI scans in all patients. The presence, size, number, and loca-tion of all hyperintense lesions in the DWI were analyzed.
Results: We classified the DWI lesions into 4 patterns; 1) single middle to large sized lesion (3 cases, 10.7%), 2) single small sized lesion (5 cases, 17.9%), 3) multiple lesions in single ar-terial territory (10 cases, 35.7%), 4) multiple disseminated lesions (10 cases, 35.7%). Single lesions were present on 8 scans (28.6%) and multiple DWI lesions were present on 20 scans (71.4%).
Conclusion: Cerebral infarction associated with malig-nancy usually have multiple and variable sized lesions. DWI patterns could provide some clues to detect malignancies when etiology of cerebral infarction is ambiguous. (Korean J Stroke 2008;10:36-40)
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KEYWORD
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CerebralInfarction, Malignancy, Diffusion-WeightedImaging
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